T 0643/96 (Bioisosterism/BEECHAM) of 14.10.1996

European Case Law Identifier: ECLI:EP:BA:1996:T064396.19961014
Date of decision: 14 October 1996
Case number: T 0643/96
Application number: 88312038.8
IPC class: C07D 453/02
Language of proceedings: EN
Distribution: B
Download and more information:
Decision text in EN (PDF, 481 KB)
Documentation of the appeal procedure can be found in the Register
Bibliographic information is available in: EN
Versions: Unpublished
Title of application: Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
Applicant name: BEECHAM GROUP PLC
Opponent name: -
Board: 3.3.01
Headnote: -
Relevant legal provisions:
European Patent Convention 1973 Art 52(1)
European Patent Convention 1973 Art 56
European Patent Convention 1973 Art 113(1)
Keywords: Inventive step - yes - chemical compounds - no pointer to claimed compounds
Catchwords:

1. The concept of bioisosterism has to be applied with caution when deciding upon inventive step (No. 4.2.3.3).

2. When deciding upon inventive step in relation to pharmacologically active compounds, what is essential is not whether a particular substructure of a chemical compound is replaced by another known isosteric one, but whether information was available on the impact of such a replacement on the pharmacological activity profile of the specific (group of) compound(s) concerned (No. 4.2.3.5).

Cited decisions:
T 0309/91
T 0548/91
T 0852/91
Citing decisions:
T 0467/94
T 0156/95
T 2402/10
T 2320/16

Source: http://www.epo.org/law-practice/case-law-appeals/recent/t960643eu1.html

Date retrieved: 17 May 2021

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