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Art. 97(3) EPC (former Art. 97(4) EPC 1973) stipulates that the decision to grant a European patent shall take effect on the date on which the mention of the grant is published in the European Patent Bulletin.
Under Art. 97(2) EPC (former Art. 97(1) EPC 1973) if the examining division is of the opinion that the European patent application or the invention to which it relates does not meet the requirements of the EPC, it shall refuse the application unless the EPC provides for a different legal consequence.
A request to withdraw an amendment is itself a request for further amendment; thus, if this request occurs after reply to the first communication from the examiner, the corresponding amendment will be admitted only if the examiner consents.