International applications relating to the aforementioned unavailable biological material and designating or electing the EPO must comply with Rule 13bis PCT in conjunction with Rule 31. That means that for sufficient disclosure of the material the deposit with a recognised depositary institution must be made not later than the international filing date, relevant information must be given in the application and the necessary indications must be furnished as required during the international phase (see also the Notice from the EPO dated 7 July 2010, OJ EPO 2010, 498).