For international applications entering the European phase with an international preliminary examination report, the examining division should carefully take into account the position taken in that IPER before deviating from it. This may be necessary where the claims have been changed, the applicant successfully refutes the objection (either of which may happen in response to the IPER, see E‑IX, 3.3.1) or the interpretation of the rules regarding unity of invention was erroneous; see further F-V, 7.1 and F‑V, 7.2 above.